AKTIVITAS ANTIOKSIDAN DAN TOKSISITAS EKSTRAK ETIL ASETAT DAN N-HEKSAN DAUN NYIREH (Xylocarpus granatum J. Koenig)

Abstract

Nyireh leaf (Xylocarpus granatum J. Koenig) is one of the plants that have bioactive potential which is efficacious as an antioxidant to ward off free radicals. This study aims to determine the antioxidant activity, and toxicity of ethyl acetate and n-hexane extracts in Nyireh leaves (Xylocarpus granatum J. Koenig). Determination of antioxidant activity was carried out using the DPPH method (2,2-Diphenyl-1-Picrylhydrazil) and toxicity using the Brine Shrimp Leathality Test (BSLT) method. The IC₅₀ results obtained for the ethyl acetat extract were 140,307 ppm, the IC₅₀ value for n-hexane extract was 148,27 ppm. The LC₅₀results obtained for the ethyl acetate extract of nyireh leaves were 28,619 ppm, while the LC₅₀ value for the n-hexane extract was 27,094 ppm. Nyireh Leaf Ethanol and N-Hexane Extracts have antioxidant activity and toxicity